发明名称 |
Water-soluble derivatives of lipophilic drugs |
摘要 |
A water-soluble reference standard is useful for immunoassays of a lipophilic drugs. The reference standard is a compound of formula (I): G-(L)n-Y (I); where G is a lipophilic drug; L is a linker which is an alkyl group or heteroalkyl group containing from 1 to 20 carbon atoms; n is 0 or 1; and Y is a water-solubilizing group such as -SO3-, -NR-SO3-, -P(=O)(OH)(O-), or -O-P(=O)(OH)(O-); where R is H or an alkyl group of 1 to 10 carbon atoms.
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申请公布号 |
US2003153096(A1) |
申请公布日期 |
2003.08.14 |
申请号 |
US20020057762 |
申请日期 |
2002.01.25 |
申请人 |
LI MIN;WU ROBERT S.;TSAI JANE S.C. |
发明人 |
LI MIN;WU ROBERT S.;TSAI JANE S.C. |
分类号 |
G01N33/531;A61K47/48;C07D243/24;C07D243/26;G01N33/53;G01N33/94;(IPC1-7):G01N33/543;C07F9/655;C07F9/651;C07F9/576 |
主分类号 |
G01N33/531 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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