发明名称 |
Human monoclonal antibody against coreceptors for human immunodeficiency virus |
摘要 |
Compositions are provided that comprise antibody against coreceptors for human immunodeficiency virus such as CCR5 and CXCR4. In particular, monoclonal human antibodies against human CCR5 are provided that bind to CCR5 with high affinity and are capable of inhibiting HIV infection at low concentrations. The antibodies can be used as prophylactics or therapeutics to prevent and treat HIV infection, for screening drugs, and for diagnosing diseases or conditions associated with interactions with HIV coreceptors.
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申请公布号 |
US2003152913(A1) |
申请公布日期 |
2003.08.14 |
申请号 |
US20020072301 |
申请日期 |
2002.02.08 |
申请人 |
HUA SHAOBING;PAULING MICHELLE H.;ZHU LI |
发明人 |
HUA SHAOBING;PAULING MICHELLE H.;ZHU LI |
分类号 |
C07K16/28;C12N5/08;(IPC1-7):C12Q1/70;A61K39/42;C07K16/10 |
主分类号 |
C07K16/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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