发明名称 |
PROCESS FOR PRODUCING (R)-3-HYDROXY-3-(2-PHENYLETHYL)HEXANOIC ACID AND ITS INTERMEDIATE |
摘要 |
A process for producing (R)-3-hydroxy-3-(2-phenylethyl)hexanoic acid characterized in that racemic 3-hydroxy-3-(2-phenylethyl)hexanoic acid is optically resolved by using an optically active amine represented by the following general formula (VIII): (VIII) wherein R2 represents 3,4- dimethoxyphenyl or 2-chlorophenyl. Thus, (R)-3-hydroxy-3-(2- phenylethyl)hexanoic acid useful as a material of drugs can be efficiently produced at a high optical purity and a relatively high total yield.
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申请公布号 |
CA2475332(A1) |
申请公布日期 |
2003.08.14 |
申请号 |
CA20022475332 |
申请日期 |
2002.10.31 |
申请人 |
SUMITOMO CHEMICAL COMPANY, LIMITED |
发明人 |
MAEDA, HIROSHI;TANAKA, MASAHIDE;ITAYA, NOBUSHIGE;KATSURA, TADASHI;IWASAKI, MITSUHIRO;MATSUI, KOZO |
分类号 |
C07C45/62;C07C45/73;C07C45/74;C07C49/213;C07C51/43;C07C51/487;C07C69/732;C07C211/29;C07C217/58;(IPC1-7):C07C51/43;C07B57/00;C07C67/343;C07C59/48 |
主分类号 |
C07C45/62 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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