发明名称 1-Glyoxlylamide indolizines for treating cancer
摘要 Disclosed is a compound represented by Structural Formula (I): Ring A is substituted or unsubstituted and optionally fused to an aryl group. Z1 and Z2 are independently =O, =S, =N-OR12 or =NR12 R1 and R2 are independently -H, an aliphatic group, a substituted aliphatic group, an unsubstituted non-aromatic heterocylic group, a substituted non-aromatic heterocylic group, an aryl group or a substituted aryl group, provided that R1 and R2 are not both -H. Alternatively, -NR1R2, taken together, is a substituted or unsubstituted non-aromatic nitrogen-containing heterocyclic group or a substituted or unsubstituted nitrogen-containing heteroaryl group. R3 is a substituted or unsubstituted aryl group or a substituted or unsubstituted aliphatic group. X is a covalent bond, -C(R4R5)-, -N(R4)-, -O-, -S-, -S(O)-, -S(O)2-, -C(=O)-, -C(=O)-N(R4)-, or -N(R4)-C(=O)-. R4 and R5 are independently -H or a substituted or unsubstituted aliphatic group. R12 is -H or a substituted or unsubstituted alkyl group.
申请公布号 US2003153759(A1) 申请公布日期 2003.08.14
申请号 US20020244088 申请日期 2002.09.13
申请人 SBR PHARMACEUTICALS CORP. 发明人 KOYA KEIZO;SUN LIJUN;ONO MITSUNORI;YING WEIWEN;LI HAO
分类号 A61K31/437;A61K31/444;A61K31/4709;A61K31/496;A61P35/00;C07D471/04;(IPC1-7):C07D455/02;A61K31/506;A61K31/474 主分类号 A61K31/437
代理机构 代理人
主权项
地址