HETERODIMERIC CONJUGATES OF NEOMYCIN-OXAZOLIDINONE, THEIR PREPARATION AND THEIR USE

摘要

The present invention relates to heterodimeric conjugates of neomycin-oxazolidinone of formula 1, their preparation and their use. Because of their heterodimeric structure, they can recognize both stems and loops of the RNA motif and show a strong binding force to certain RNAs. Accordingly, they can be effectively used as an antiviral agent or an antibacterial agent with enhanced pharmaceutical efficacy and reduced side effect. Formula (I) Wherein, Ac and n are as defined in the description.