发明名称 |
METHOD AND APPARATUS FOR PERFORMING SUBMICROLITER REACTIONS WITH NUCLEIC ACIDS OR PROTEINS |
摘要 |
Methods for preparing nanoscale reactions using nucleic acids or proteins are presented, Nucleic acids are captured saturably, yet reversibly, on the internal surface of the reaction chamber, typically a capillary. Excess nucleic acid is removed and the reaction is performed directly within the capillary. Proteins are captured specifically and saturably on the modified inner surface of the reaction chamber, typically a capillary. Excess protein is removed and the reaction is performed directly within the capillary. Devices for effecting the methods of the invention and a system designed advantageously to utilize the methods for high throughput reactions involving nucleic acids or proteins are also provided. |
申请公布号 |
WO03066667(A2) |
申请公布日期 |
2003.08.14 |
申请号 |
WO2003US03986 |
申请日期 |
2003.02.07 |
申请人 |
AMERSHAM BIOSCIENCES SV CORP |
发明人 |
JOVANOVICH STEVAN BOGDAN;SALAS-SOLANO OSCAR;LI JENG-THUN |
分类号 |
G01N21/78;B01L3/00;B01L3/02;B01L7/00;C12N15/09;C12P1/00;C12Q1/00;C12Q1/68;C40B40/06;C40B60/14 |
主分类号 |
G01N21/78 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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