发明名称 |
Nucleic acid encoding a chimeric polypeptide |
摘要 |
A therepeutic method whereby an individual suspected of having an alpha-galactosidase A deficiency, such as Fabry disease, is treated either with (1) human cells that have been genetically modified to overexpress and secrete human alpha-gal A, or (2) purified human alpha-gal A obtained from cultured, genetically modified human cells.
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申请公布号 |
US2003152560(A1) |
申请公布日期 |
2003.08.14 |
申请号 |
US20020318905 |
申请日期 |
2002.12.12 |
申请人 |
TRANSKARYOTIC THERAPIES INC., A MASSACHUSETTS CORPORATION |
发明人 |
SELDEN RICHARD F.;BOROWSKI MARIANNE;GILLISPIE FRANCES P.;KINOSHITA CAROL M.;TRECO DOUGLAS A.;WILLIAMS MELANIE D. |
分类号 |
A61K38/00;C07K14/61;C12N5/08;C12N9/40;C12P21/04;(IPC1-7):A61K48/00;C12Q1/68;C07H21/04;C12P21/02 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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