HETERODIMERIC CONJUGATE OF NEOMYCIN-OXAZOLIDINONE AND PREPARATION METHOD AND USE THEREOF

摘要

PURPOSE: Provided is a heterodimeric conjugate of neomycin-oxazolidinone which is useful as an antiviral agent and an antibacterial agent. Also, provided are the preparation method and use thereof. CONSTITUTION: A heterodimeric conjugate of neomycin-oxazolidinone is represented by the formula(1), wherein n is an integer of 2-10 and Ac represents an acetyl group. It is characterized by specifically bonding to 16S rRNA, RRE, RNA or 23S rRNA.