发明名称 |
IL-16 antagonist peptides and DNA encoding the peptides |
摘要 |
The present invention has found that a series of peptides having sequences that substantially correspond to specific regions of the C-terminus of IL-16 can inhibit the activity of IL-16. The present invention has demonstrated that such IL-16-inhibiting peptides can be as short as 4 amino acids in length. Based on these discoveries, the present invention provides IL-16 antagonist peptides and the use thereof for the treatment of IL-16 mediated disorders such as certain inflammatory diseases. |
申请公布号 |
US2003153504(A1) |
申请公布日期 |
2003.08.14 |
申请号 |
US20030358627 |
申请日期 |
2003.02.05 |
申请人 |
CENTER DAVID M.;CRUIKSHANK WILLIAM W.;KORNFELD HARDY |
发明人 |
CENTER DAVID M.;CRUIKSHANK WILLIAM W.;KORNFELD HARDY |
分类号 |
C12N15/09;A61K31/56;A61K38/00;A61K39/395;A61P1/04;A61P5/14;A61P11/06;A61P25/00;A61P29/00;A61P31/22;C07K5/10;C07K5/11;C07K7/06;C07K7/08;C07K14/54;C07K16/44;(IPC1-7):A61K38/10;A61K38/08 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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