| 发明名称 |
WATER SOLUBLE PHENYLGLYCINE DERIVATIVES |
| 摘要 |
The invention is concerned with novel water soluble N-4-carbamimidoyl-phenyl- glycine derivatives of Formula I wherein R1 to R4 and n are as defined in the description and in the claims, as well as physiologically acceptable salts thereof. These compounds inhibit the formation of coagulation factors Xa, Ixa and thrombin induced by factor VIIa and tissue factor and can be used as medicaments.
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| 申请公布号 |
WO03066588(A1) |
申请公布日期 |
2003.08.14 |
| 申请号 |
WO2003EP00937 |
申请日期 |
2003.01.30 |
| 申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
ALIG, LEO;GROEBKE ZBINDEN, KATRIN;OBST, ULRIKE |
| 分类号 |
A61K31/445;A61K31/4465;A61P7/02;A61P9/00;A61P9/10;A61P29/00;A61P35/00;C07D211/22;C07D211/42;C07D211/46;(IPC1-7):C07D211/22;A61K31/446 |
主分类号 |
A61K31/445 |
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