发明名称 |
NOVEL 3-ARYL-2,5-DIHYDROXY-1,4-BENZOQUINONE DERIVATIVES, THEIR PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME |
摘要 |
The invention concerns a compound of formula (I), wherein: R1 and R2, identical or different, represent each a hydrogen atom or an acyl or alkyl group; Ar represents an aryl or heteroaryl group; A represents a group selected from formula (II); R4 represents a hydrogen atom or an alkyl group; R5 represents a hydrogen atom or a group selected among alkyl, aryl and heteroaryl; R3 represents an aryl, heteroaryl, dicyclopropylmethyl or benzhydryl group, or A-R3 represents an optionally substituted naphthyl group, excluding 2,5-dihydroxy-3-(4-methoxyphenyl)-6-(2-phenylethenyl)-1,4-benzoquinone, 2,5-dihydroxy-3-(4-methoxyphenyl)-6-(2-naphthyl)-1,4-benzoquinone, and 2,5-dihydroxy-3-(2-naphthyl)-6-phenyl-1,4-benzoquinone. The inventive compound is useful for preparing medicines.
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申请公布号 |
WO03066561(A1) |
申请公布日期 |
2003.08.14 |
申请号 |
WO2003FR00331 |
申请日期 |
2003.02.04 |
申请人 |
LES LABORATOIRES SERVIER;DASSONVILLE, ALEXANDRA;BRETECHE, ANNE;DUFLOS, MURIEL;LE BAUT, GUILLAUME;PFEIFFER, BRUNO;RENARD, PIERRE;LEVENS, NIGEL;HUSSON-ROBERT, BERNADETTE |
发明人 |
DASSONVILLE, ALEXANDRA;BRETECHE, ANNE;DUFLOS, MURIEL;LE BAUT, GUILLAUME;PFEIFFER, BRUNO;RENARD, PIERRE;LEVENS, NIGEL;HUSSON-ROBERT, BERNADETTE |
分类号 |
A61K31/122;A61K31/222;A61K31/4402;A61P3/10;C07C45/00;C07C45/28;C07C46/00;C07C46/10;C07C50/28;C07C50/30;C07D213/50;(IPC1-7):C07C50/28 |
主分类号 |
A61K31/122 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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