发明名称 |
Variant of modified virus of Ankara vaccine type |
摘要 |
<p>The present invention provides an attenuated virus, which is derived from Modified Vaccinia Ankara virus and which is characterized by the loss of its capability to reproductively replicate in human cell lines. It further describes recombinant viruses derived from this virus and the use of the virus or its recombinants as medicament or vaccine. Additionally, a method for inducing an immune response even in immuno-compromised patients, patients with pre-existing immunity to the vaccine virus or patients undergoing antiviral therapies is provided.</p> |
申请公布号 |
CZ20031366(A3) |
申请公布日期 |
2003.08.13 |
申请号 |
CZ20030001366 |
申请日期 |
2001.11.22 |
申请人 |
BAVARIAN NORDIC A/S |
发明人 |
CHAPLIN PAUL;HOWLEY PAUL;MEISINGER CHRISTINE |
分类号 |
C12N15/09;A61K39/275;A61K39/285;A61K39/39;A61K48/00;A61P37/04;C07K14/16;C12N5/10;C12N7/00;C12N7/01;C12N7/02;C12N7/04;C12N15/39;C12N15/863;C12P21/02;C12R1/93;(IPC1-7):C12N15/86 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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