发明名称 |
Process for preparing N-(substituted phenyl)-3-alkyl,-aryl- and -heteroaryl sulfonyl-2-hydroxy-2-alkyl-and ?haloalkyl propanamide compounds |
摘要 |
<p>The present invention provides an improved process for the preparation of N-(substituted phenyl)-3-alkyl-, aryl- and heteroarylsulfonyl-2-hydroxy-2-alkyl- and haloalkylpropanamide compounds of formula I that exhibit antiandrogenic activity and are useful in the treatment of malignant or benign prostatic disease or of androgen dependent disease conditions such as acne, hirsutism or seborrhea.</p> |
申请公布号 |
CZ20030836(A3) |
申请公布日期 |
2003.08.13 |
申请号 |
CZ20030000836 |
申请日期 |
2001.09.17 |
申请人 |
BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
CHEN BANG-CHI;SUNDEEN JOSEPH E.;ZHAO RULIN |
分类号 |
C07D301/14;C07C253/30;C07C255/60;C07C315/02;C07C317/46;C07C319/14;C07C323/52;C07C323/60;C07D303/48;(IPC1-7):C07C317/46;C07C323/62 |
主分类号 |
C07D301/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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