发明名称 |
Atorvastatin hemi-calcium form VII |
摘要 |
The present invention provides a novel form of atorvastatin hemi-calcium designated Form VII and novel processes for its preparation whereby another crystalline form of atorvastatin hemi-calcium is suspended in ethanol, preferably absolute ethanol, and is converted to the new form, which is then isolated. The present invention further provides a method of reducing the plasma low density lipoprotein level in patients suffering from or susceptible to hypercholesterolemia and compositions and dosage forms for practicing the invention.
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申请公布号 |
US6605636(B2) |
申请公布日期 |
2003.08.12 |
申请号 |
US20010992746 |
申请日期 |
2001.11.05 |
申请人 |
TEVA PHARMACEUTICAL INDUSTRIES LTD. |
发明人 |
ARONHIME JUDITH;LIDOR-HADAS RAMY;NIDDAM VALERIE;LIFSHITZ REVITAL |
分类号 |
A61K31/40;A61P1/06;A61P3/06;A61P9/10;A61P43/00;C07D207/34;C07D405/06;(IPC1-7):A61K31/40;C07D207/335 |
主分类号 |
A61K31/40 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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