Conduit designs and related methods for optimal flow control

摘要

A bypass conduit and related methods include implanting a bypass in the heart between a heart chamber and an at least partially occluded artery to directly flow blood from the chamber to the artery. The bypass conduit is configured to have a higher resistance to blood flow in a first direction than in a second direction without any active flow control mechanism. The bypass conduit may have a first end defining a first opening and a second end defining a second opening and a wall extending between the two ends that defines a lumen extending between the two openings. The ends and the wall of the conduit are configured to have a higher resistance to blood flow in a first direction than in a second direction. A method of bypassing an at least partially occluded artery includes determining a resistance to blood flow of the artery at a location of an at least partial occlusion and selecting a conduit having a configuration based on the resistance to blood flow of the artery at the location of the at least partial occlusion. The method further includes implanting the conduit in a heart wall between the heart chamber and the artery downstream of the at least partial occlusion to directly flow blood between the chamber and the artery.