OPTICALLY ACTIVE 2-(1-AMINOALKYL)ANILINE, ITS OPTICALLY ACTIVE SUCCINIC ACID SALT, AND METHOD FOR PRODUCING THEM

摘要

PROBLEM TO BE SOLVED: To provide a synthetic intermediate obtaining a treating agent of ischemic heart diseases, in a good yield and in a high optical purity. SOLUTION: An optically active compound expressed by general formula (1) (wherein R1is a lower alkyl; R2is H, a halogen atom or the like; and *shows as asymmetric carbon atom), and a salt of the compound expressed by the general formula (1) with a compound expressed by general formula (2) (wherein, R3is H, a lower alkyl or the like) is provided. The method for producing the salt of the optically active compound expressed by the general formula (1) with the compound expressed by the general formula (2) is provided by a reaction of a mixture of optical isomers of the compound expressed by the general formula (1) with the optically active compound expressed by the general formula (2) in a solvent. COPYRIGHT: (C)2003,JPO