发明名称 |
DNA-kodende for prolyl-endopeptidase samt dets anvendelse |
摘要 |
The invention concerns DNA encoding prolylendopeptidase, hybrid vectors containing such DNA, transformed hosts capable of expressing prolylendopeptidase, a process for the production of prolylendopeptidase comprising the steps of: culturing a host organism transformed with an expression vector comprising a DNA coding for prolylendopeptidase and optionally, recovering the produced prolylendopeptidase; and a process for the production of a C-terminal amidated peptide from two precursors thereof, comprising the steps of: placing the two precursors in contact with a prolylendopeptidase in a medium to convert the precursor peptides to the C-terminal amidated peptide, and recovering the resulting C-terminal amidated peptide. |
申请公布号 |
DK0524906(T3) |
申请公布日期 |
2003.08.11 |
申请号 |
DK19920810537T |
申请日期 |
1992.07.15 |
申请人 |
NOVARTIS AG |
发明人 |
INAOKA, TETSUYA, DR.;KOKUBO, TOSHIO, DR.;TSURU, DAISUKE, PROF.;YOSHIMOTO, TADASHI, PROF. |
分类号 |
C12N15/09;C12N1/21;C12N9/52;C12N15/57;C12P21/02;C12R1/20 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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