发明名称 |
Nucleotide and amino acid sequences of asporins |
摘要 |
Mouse asporin protein and nucleic acid sequences are disclosed. The protein contains a unique aspartic acid region near the N-terminus. The central domain contains ten leucine rich repeats. Sequences consistent with other class I small leucine rich repeat proteoglycans (SLRP) are also observed. Methods of use for the protein include regulating the complement system, inhibiting fibrosis formation, regulating the growth of endothelial cells and angiogenesis, regulating or inhibiting the growth of cancer cells, and regulating the functions of neuromuscular junctions.
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申请公布号 |
US2003148351(A1) |
申请公布日期 |
2003.08.07 |
申请号 |
US20020319130 |
申请日期 |
2002.12.13 |
申请人 |
HENRY STEPHEN P.;HOOK A.O. MAGNUS;MAYNE RICHARD |
发明人 |
HENRY STEPHEN P.;HOOK A.O. MAGNUS;MAYNE RICHARD |
分类号 |
A61K38/00;C07K14/47;(IPC1-7):C12Q1/68;G01N33/574;C07H21/04;C12P21/02;C12N5/06 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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