发明名称 PTPase INHIBITORS AND METHODS OF USING THE SAME
摘要 The present invention relates to protein tyrosine phosphatase ("PTPase") inhibitors, and the use of PTPase inhibitors and PTPase inhibitors in combination with cytokines to treat diseases. Leishmaniasis agents have surprisingly and unexpectedly been found to be potent PTPase inhibitors. Examples of leishmaniasis agents that are also PTPase inhibitors include, but are not limited to, pentavalent antimonial compounds, imidazole compounds, and diamidine compounds. Therapeutic compositions and methods are provided that make use of these compounds to treat diseases.
申请公布号 WO03063788(A2) 申请公布日期 2003.08.07
申请号 WO2003US02770 申请日期 2003.01.30
申请人 THE CLEVELAND CLINIC FOUNDATION;YI, TAOLIN 发明人 YI, TAOLIN
分类号 A61K31/29;A61K31/496;A61K31/555;A61K38/19 主分类号 A61K31/29
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