发明名称 |
Process for the production of amorphous atorvastatin calcium |
摘要 |
A process for the preparation of amorphous atorvastatin calcium and hydrates thereof which comprises: (a) dissolving crystalline atorvastatin calcium in a non-hydroxylic solvent; (b) adding a non-polar hydrocarbon anti-solvent or adding the dissolved atorvastatin to the non-polar anti-solvent to precipitate out atorvastatin calcium; and (c) removing the solvent by filtration to afford amorphous atorvastatin calcium.
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申请公布号 |
US2003149279(A1) |
申请公布日期 |
2003.08.07 |
申请号 |
US20030378574 |
申请日期 |
2003.03.03 |
申请人 |
KUMAR YATENDRA;THAPER RAJESH KUMAR;KUMAR S. M. DILEEP |
发明人 |
KUMAR YATENDRA;THAPER RAJESH KUMAR;KUMAR S. M. DILEEP |
分类号 |
C07D207/34;(IPC1-7):C0727/33 |
主分类号 |
C07D207/34 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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