发明名称 |
Identification of neural defects associated with the nucleosomal assembly protein 112 gene |
摘要 |
A method for screening neural system defects in a human comprises: (A) providing chromosomal material from the human; (B) detecting a modification of the NAP1L2 gene in the chromosomal material, wherein the modification is selected from a) substitution, b) deletion, c) frame-shift, or d) insertion that causes a loss of biological function in the NAP1L2 gene; and (C) correlating the modification of the gene with a potential for a neural system defect. The method can also be practiced with the mouse Nap1l2 gene.
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申请公布号 |
US2003148274(A9) |
申请公布日期 |
2003.08.07 |
申请号 |
US20010847665 |
申请日期 |
2001.05.03 |
申请人 |
ROGNER UTE;SPYROPOULOS DEMETRI;ROUGEULLE CLAIRE;AVNER PHILIP R |
发明人 |
ROGNER UTE;SPYROPOULOS DEMETRI;ROUGEULLE CLAIRE;AVNER PHILIP R |
分类号 |
G01N33/48;A61K45/00;A61P25/00;A61P35/00;C12N5/10;C12N15/09;C12Q1/68;G01N33/15;G01N33/50;G01N33/53;(IPC1-7):C12Q1/68;C07H21/04 |
主分类号 |
G01N33/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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