发明名称 |
Virus-free vesicles for delivery of functional membrane bound proteins |
摘要 |
The present invention is directed to methods for producing virus-free vesicles containing functional membrane proteins, and uses thereof. Preferably the virus-free vesicles contain a type II transmembrane protein which is a member of the TNF superfamily. The vesicles maintain the protein in its native conformation, thus eliminating the problems related to the solubility of these proteins when produced without presence of membrane component.
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申请公布号 |
US2003148454(A1) |
申请公布日期 |
2003.08.07 |
申请号 |
US20020287278 |
申请日期 |
2002.11.04 |
申请人 |
TRUSTEES OF BOSTON UNIVERSITY |
发明人 |
MARSHAK-ROTHSTEIN ANN;JU SHYR-TE;JODO SATOSHI;HOHLBAUM ANDREAS MICHAEL |
分类号 |
C07K14/705;C12P21/02;(IPC1-7):C12P21/02;C12N1/00;C12N5/06;C07K14/525 |
主分类号 |
C07K14/705 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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