The present invention provides a use of a whey protein hydrolysate in the manufacture of a medicament or an edible product useful to lower low-density ipoprotein LDL cholesterol in a mammal. The present invention also provides an article, including: a an edible product including a whey protein hydrolysate and b packaging material, wherein the packaging material is marked to indicate that the product gives the benefit of lowering cholesterol. The present invention further provides methods and treatments for a mammal to lower low-density lipoprotein LDL cholesterol, including feeding to the mammal a whey protein hydrolysate in amounts and at intervals effective to lower LDL cholesterol.