发明名称 HETEROCYCLIC TRIPEPTIDES AS HEPATITIS C INHIBITORS
摘要 Compounds of formula (I):wherein R<sp>1</sp> is hydroxyl or sulfonamide derivative; R<sp>2</sp> is t−butyl or −CH<sb>2</sb>−C(CH<sb>3</sb>)<sb>3</sb> or −CH<sb>2</sb>−cyclopentyl; R<sp>3 </sp>is t−butyl or cyclohexil and R<sp>4</sp> is cyclobutyl, cyclopentyl or cyclohexyl; or a pharmaceutically acceptable salt thereof, are described as useful as inhibitor of the HCV NS3 protease.<sb> </sb>
申请公布号 WO03064416(A1) 申请公布日期 2003.08.07
申请号 WO2003CA00091 申请日期 2003.01.24
申请人 BOEHRINGER INGELHEIM INTERNATIONAL GMBH;LLINAS-BRUNET, MONTSE;BAILEY, MURRAY, D.;GHIRO, ELISE 发明人 LLINAS-BRUNET, MONTSE;BAILEY, MURRAY, D.;GHIRO, ELISE
分类号 C12N15/09;A61K31/7056;A61K38/00;A61K38/21;A61P1/16;A61P31/00;A61P31/14;C07D417/14;C07K5/08;C07K5/083;C07K5/087;(IPC1-7):C07D417/14;A61K31/47;C07K4/00 主分类号 C12N15/09
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