HETEROCYCLIC TRIPEPTIDES AS HEPATITIS C INHIBITORS
摘要
Compounds of formula (I):wherein R<sp>1</sp> is hydroxyl or sulfonamide derivative; R<sp>2</sp> is t−butyl or −CH<sb>2</sb>−C(CH<sb>3</sb>)<sb>3</sb> or −CH<sb>2</sb>−cyclopentyl; R<sp>3 </sp>is t−butyl or cyclohexil and R<sp>4</sp> is cyclobutyl, cyclopentyl or cyclohexyl; or a pharmaceutically acceptable salt thereof, are described as useful as inhibitor of the HCV NS3 protease.<sb> </sb>
申请公布号
WO03064416(A1)
申请公布日期
2003.08.07
申请号
WO2003CA00091
申请日期
2003.01.24
申请人
BOEHRINGER INGELHEIM INTERNATIONAL GMBH;LLINAS-BRUNET, MONTSE;BAILEY, MURRAY, D.;GHIRO, ELISE