发明名称 |
PEPTIDE DERIVATIVES AND THEIR PHARMACEUTICALLY ACCEPTABLE SALTS, PROCESSES FOR PREPARATION OF BOTH, AND USE THEREOF |
摘要 |
<p>The present invention provides a peptide derivative of formula (I)
<Chemistry id="chema01" num="0001"><Image id="ia01" he="43" wi="99" file="IMGA0001.TIF" imgContent="chem" imgFormat="TIFF" /></Chemistry> wherein X is -CHOH- or -CO-; R<Sup>1</Sup> and R<Sup>2</Sup> are hydrogen or substituted oxycarbonyl; R<Sup>3</Sup> is substituted oxycarbonyl; R<Sup>4</Sup> is hydroxyl, lower alkoxy, optionally substituted piperazinyl or the like; R<Sup>5</Sup> is a R-group side chain of an α-amino acid optionally protected by a protective group, R<Sup>6</Sup> is hydroxyl, lower alkoxy or the like; m is 0 or 1; and n is an integer of 2 to 6; or a pharmaceutically acceptable salt thereof. The present invention further provides a production process and use thereof.</p> |
申请公布号 |
EP1333024(A1) |
申请公布日期 |
2003.08.06 |
申请号 |
EP20010980959 |
申请日期 |
2001.11.02 |
申请人 |
TAIHO PHARMACEUTICAL CO., LTD. |
发明人 |
YAMAMOTO, KENJI;SUDA, YOSHIMITSU;ASAO, TETSUJI |
分类号 |
A61K38/00;A61P1/02;A61P43/00;C07C271/22;C07D295/185;C07K5/072;C07K5/093;(IPC1-7):C07C271/22;C07D295/18;C07K5/06;A61K31/27;A61K31/495;A61K38/06 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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