摘要 |
PROBLEM TO BE SOLVED: To provide a method for manufacturing simply and in a high yield an N-long chain acyl neutral amino acid of high purity useful for the manufacture of a detergent, and the like. SOLUTION: This method for manufacturing the N-long chain acyl neutral amino acid comprises reacting a neutral amino acid such as glycine,γ- aminobutyric acid, alanine with a saturated or unsaturated 8-22C fatty acid halide, where the reaction is carried out in the presence of a base in a mixture of at least one hydrophilic organic solvent selected from the group consisting of acetone, acetonitrile, a 3-4C secondary alcohol and a 4C tertiary alcohol (for example, isopropanol, sec-butanol, tert-butanol and the like) with water. COPYRIGHT: (C)2003,JPO
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