| 发明名称 |
Crystalline monohydrate of tiotropium bromide, method for producing the same, pharmaceutical composition comprising same and the use thereof |
| 摘要 |
Crystalline monohydrate (I) of tiotropium bromide ((1alpha ,2beta ,4beta ,5alpha ,7beta )-7-(2-hydroxy-2,2-di(2-thienyl)acetoxy)-9,9-dimethyl-3-oxa-9-azonia-tricyclo[3.3.1.0 2>.4]nonane bromide) is new. An independent claim is also included for the preparation of (I). ACTIVITY : Antiinflammatory; antiasthmatic. MECHANISM OF ACTION : Anticholinergic. |
| 申请公布号 |
SK4362003(A3) |
申请公布日期 |
2003.08.05 |
| 申请号 |
SK20030000436 |
申请日期 |
2001.09.28 |
| 申请人 |
BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG |
发明人 |
BANHOLZER ROLF;GRAULICH MANFRED;KULINNA CHRISTIAN;MATHES ANDREAS;MEISSNER HELMUT;SIEGER PETER;SPECHT PETER;TRUNK MICHAEL |
| 分类号 |
A61K9/14;A61K9/72;A61K31/439;A61K31/46;A61P11/00;A61P11/06;A61P43/00;C07D451/10;C07D451/14 |
主分类号 |
A61K9/14 |
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