Bicyclic cyclohexylamines and their use as NMDA receptor antagonists

摘要

Described are bicycle-substituted cyclohexylamines of Formula I and their pharmaceutically acceptable salts thereof:The compounds are antagonists of NMDA receptor channel complexes useful for treating cerebral vascular disorders such as, for example, cerebral ischemia, cardiac arrest, stroke, and Parkinson's disease. The substituents are defined in the specification.