| 发明名称 |
Combination viral-based and gene-based therapy of tumors |
| 摘要 |
The present invention relates to viral mutants and methods of using these viral mutants for selectively killing neoplastic cells. The viral mutants of the invention are capable of selectively killing neoplastic cells by a combination of viral mediated oncolysis and anti-cancer ("suicide") gene therapy.
|
| 申请公布号 |
US6602499(B1) |
申请公布日期 |
2003.08.05 |
| 申请号 |
US19990302952 |
申请日期 |
1999.04.30 |
| 申请人 |
THE GENERAL HOSPITAL CORPORATION |
发明人 |
CHIOCCA E. ANTONIO;BREAKEFIELD XANDRA O. |
| 分类号 |
A61K35/76;A61K47/48;A61K48/00;C12N7/00;C12N15/869;(IPC1-7):A61K35/00;C12N15/63;C12N5/00 |
主分类号 |
A61K35/76 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
