发明名称 |
Recombinant anti-VLA-4 antibody molecules |
摘要 |
The present invention disclosed recombinant anti-VLA-4 antibody molecules, including humanized recombinant anti-VLA-4 antibody molecules. These antibodies are useful in the treatment of specific and non-specific inflammation, including asthma and inflammatory bowel disease. In addition, the humanized recombinant anti-VLA-4 antibodies disclosed can be useful in methods of diagnosing and localizing sites of inflammation.
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申请公布号 |
US6602503(B1) |
申请公布日期 |
2003.08.05 |
申请号 |
US19950454899 |
申请日期 |
1995.05.31 |
申请人 |
BIOGEN, INC. |
发明人 |
LOBB ROY R.;CARR FRANK J.;TEMPEST PHILIP R. |
分类号 |
C12N15/09;A61K38/00;A61K39/395;A61P7/02;A61P9/10;A61P11/00;A61P11/06;A61P29/00;A61P31/00;A61P35/00;A61P35/02;A61P37/02;C07K14/78;C07K16/18;C07K16/28;C07K19/00;C12N1/15;C12N1/19;C12N1/21;C12N5/00;C12N5/10;C12N15/13;C12P21/02;C12P21/08;C12R1/91;G01N33/53;G01N33/577;(IPC1-7):A61K39/395;C12N5/12 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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