| 摘要 |
The invention relates to pharmaceutical compositions comprising active glimepiride and metformin substances or the salts thereof, such as hydrochloride, succinate, fumarate, etc., which are used to control blood glucose in patients with type 2 diabetes. Clinical studies, which were carried out in order to demonstrate the effectiveness of said combination, have shown that the effect produced by the two drugs is not only additive but also synergetic in comparison with the monotherapy which uses only one of the drugs from the combination. As a result, the use of said combination is suggested as an effective and safe therapy for the control of blood glucose in patients with type 2 diabetes. According to the invention, different proportions of the active substances can be used so that the combination suits the different requirements of each patient. |
