发明名称 |
Process for preparing citalopram |
摘要 |
Process for preparing purified citalopram or one of its salts that comprises the purification of citalopram by selective extractions of citalopram or of its impurities with organic solvents and water under specific conditions of pH and temperature. The crude citalopram can be prepared by a process that comprises reacting 1-[3-(dimethylamine)propyl]-1-(4-fluorophenyl)-1,3-dihydro-5-bromoisobenzofuran with copper cyanide.
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申请公布号 |
US2003144534(A1) |
申请公布日期 |
2003.07.31 |
申请号 |
US20030351289 |
申请日期 |
2003.01.24 |
申请人 |
COPPI LAURA;GASANZ GUILLEN YOLANDA;CAMPON PARDO JULIO |
发明人 |
COPPI LAURA;GASANZ GUILLEN YOLANDA;CAMPON PARDO JULIO |
分类号 |
C07D307/87;(IPC1-7):C07D307/87 |
主分类号 |
C07D307/87 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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