| 发明名称 |
POLYALKYLENE GLYCOL WITH MOIETY FOR CONJUGATING BIOLOGICALLYACTIVE COMPOUND |
| 摘要 |
The biological activity of biologically active compounds and reduction of toxicity is addressed by the conjugation of a biologically active compound with an activated polyalkylene glycol having a moiety which covalently bonds to the compound. A pharmaceutical composition containing the polyalkylene glycol conjugate and a carrier, and a method of treating a patient by the administration of a composition with the polyalkylene glycol conjugate are described. |
| 申请公布号 |
CA2473526(A1) |
申请公布日期 |
2003.07.31 |
| 申请号 |
CA20032473526 |
申请日期 |
2003.01.17 |
| 申请人 |
BIOGEN IDEC MA INC. |
发明人 |
BAKER, DARREN P.;HESS, DONNA M.;LIN, EDWARD Y.;PETTER, RUSSELL C.;LIN, KOCHUNG;CHEN, LING LING;PEPINSKY, R. BLAKE |
| 分类号 |
A61K31/522;A61K31/7056;A61K31/7072;A61K38/21;A61K38/31;A61K39/29;A61K45/06;A61K47/30;A61K47/48;A61K51/06;A61P31/12;A61P31/14;C08G59/14;C08G65/32;C08G65/329;C08L71/02;C11D3/386 |
主分类号 |
A61K31/522 |
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