发明名称 3-(IMIDAZOLYL)-2-ALKOXYPROPANOIC ACIDS AS TAFIA INHIBITORS
摘要 Compounds according to formula (I) wherein n is 0-3, R<sp>1</sp> is optionally substituted C<sb>1-6</sb> alkyl, C<sb>2-6</sb> alkenyl, or C<sb>2-6</sb> alkynyl, Heterocycle, Aromatic heterocycle, Aryl or hydrogen and R<sp>2</sp>, R<sp>3</sp>, R<sp>4</sp>, R<sp>5</sp>, R<sp>6</sp>, R<sp>7</sp>, R<sp>8</sp> and R<sp>9</sp> are each independently selected from hydrogen and optionally substituted C <sb>1-6</sb> alkyl, or R<sp>5</sp> and R<sp>8</sp> are an alkylene chain, are novel. They are useful in the treatment of thrombotic conditions and other pathologies associated with fibrin deposition.
申请公布号 WO03061652(A1) 申请公布日期 2003.07.31
申请号 WO2003IB00060 申请日期 2003.01.10
申请人 PFIZER LIMITED;ALLERTON, CHARLOTTE, MOIRA, NORFOR;BULL, DAVID, JOHN;BUNNAGE, MARK, EDWARD;MAGUIRE, ROBERT, JOHN;STEELE, JOHN;PFIZER INC. 发明人 ALLERTON, CHARLOTTE, MOIRA, NORFOR;BULL, DAVID, JOHN;BUNNAGE, MARK, EDWARD;MAGUIRE, ROBERT, JOHN;STEELE, JOHN
分类号 C07D233/64;A61K;A61K31/4172;A61K31/4178;A61K31/4439;A61P;A61P7/02;A61P9/10;A61P17/02;A61P19/04;A61P29/00;A61P35/00;A61P41/00;A61P43/00;C07D;C07D233/54;C07D401/04;C07D403/12;(IPC1-7):A61K31/417;A61K31/417 主分类号 C07D233/64
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