STIMULATION OF BONE GROWTH AND CARTILAGE FORMATION WITH THROMBIN PEPTIDE DERIVATIVES
摘要
<p num="1"><br/><br/><br/>Disclosed is a method of stimulating bone growth at a site in a subject in <br/>need of osteoinduction or cartilage repair. The method comprises the step of <br/>administering a therapeutically effective amount of an agonist of the non-<br/>proteolytically activated thrombin receptor to the site. Also disclosed is a <br/>method of stimulating the proliferation and expansion of chrondroxytes in <br/>vitro. The method comprises culturing chrondrocytes in the presence of a <br/>stimulating amount of an NPAR agonist.<br/>
申请公布号
CA2511257(A1)
申请公布日期
2003.07.31
申请号
CA20022511257
申请日期
2002.01.17
申请人
THE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
发明人
YANG, JINPING;CROWTHER, ROGER S.;SIMMONS, DAVID J.;CARNEY, DARRELL H.;REDIN, WILLIAM R.;BERGMANN, JOHN;STIERNBERG, JANET
