发明名称 PTERIDINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF
摘要 The invention relates to compounds of general formula (I), in which R1 represents a piperazino, p-phenylendiamine, 2,5-diazabicyclo-2.2.1-heptane, 2,5-diazabicyclo-2.2.2-octane, or 3,8-diazabicyclo-3.2.1-octane residue, eac h of which can be substituted with at least one substituent, R2, R4, which are identical, represent a pyrrolidino, thiazolidine, oxazolidine, or imidazolidine residue, each of which can be substituted with at least one substituent, R3 represents an alkyl, alkoxy, alkylmercapto, or alkylamino residue, each of which can be substituted with at least one substituent, and the acid addition salts thereof. Said pteridine derivatives are suitable as phosphodiesterase inhibitors and therefore for the prophylaxis and/or therap y of thrombo-embolic, neuro-degenerating diseases, inflammatory diseases, asthmatic diseases, and hemato-oncological diseases.
申请公布号 CA2511238(A1) 申请公布日期 2003.07.31
申请号 CA20032511238 申请日期 2003.01.23
申请人 FAUSTUS FORSCHUNGS CIE. TRANSLATIONAL CANCER RESEARCH GMBH 发明人 MERZ, KARL-HEINZ;EISENBRAND, GERHARD
分类号 C07D475/00;A61K31/519;A61P7/02;A61P11/06;A61P25/00;A61P29/00;A61P35/00;A61P43/00;C07D475/08;(IPC1-7):C07D475/08;A61K31/505 主分类号 C07D475/00
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