发明名称 |
Treatment for ischemic stroke |
摘要 |
The present invention relates to a combination of [7-(1H-imidazol-1-yl)-6-nitro-2,3-dioxo-3,4-dihydroquinoxalin-1 (2H)-yl]acetic acid or a salt or hydrate thereof or, preferably, zonampanel together with a tissue plasminogen activator for the therapy of ischemic stroke or for the improvement of neurological symptom accompanied by cerebral infarction, to a method of administration thereof and to a method of therapy therefor. The combination of the present invention showed better effect of reducing the infarct volume than administration of a single component. Therefore, the combination of the present invention is useful as a therapy for ischemic stroke.
|
申请公布号 |
US2003144295(A1) |
申请公布日期 |
2003.07.31 |
申请号 |
US20020307918 |
申请日期 |
2002.12.03 |
申请人 |
YAMANOUCHI PHARMACEUTICAL CO., LTD. |
发明人 |
SUZUKI MASANORI;SASAMATA MASAO;SUMII TOSHIHISA;LO ENG H. |
分类号 |
C07D403/04;A61K31/498;A61K38/00;A61K38/49;A61K45/00;A61K45/06;A61P7/02;A61P9/10;A61P25/00;A61P43/00;(IPC1-7):A61K31/498 |
主分类号 |
C07D403/04 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|