| 发明名称 |
Hepatitis E virus vaccine and method |
| 摘要 |
Antigen and antibody vaccine composition effective in preventing hepatitis E virus (HEV) infection are disclosed. The antigen composition includes a peptide corresponding to a carboxyl terminal end region of the capsid protein encoded by the second open reading frame 2 of the HEV genome. The composition is effective in preventing HEV infection after vaccination. The antibody composition contains an antibody effective to block HEV infection of human primary hepatocytes in culture.
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| 申请公布号 |
US2003143241(A1) |
申请公布日期 |
2003.07.31 |
| 申请号 |
US20020165868 |
申请日期 |
2002.06.06 |
| 申请人 |
GENELABS TECHNOLOGIES, INC. |
发明人 |
REYES GREGORY R.;BRADLEY DANIEL W.;TWU JR-SHIN;PURDY MICHAEL A.;TAM ALBERT W.;KRAWCZYNSKI KRZYSZTOF Z.;YARBOUGH PATRICE O. |
| 分类号 |
C12N15/09;A61K38/00;A61K39/00;A61K39/29;A61K39/395;A61P31/12;C07K14/08;C07K16/10;C12N15/51;C12P21/08;C12Q1/70;G01N33/576;(IPC1-7):A61K39/29 |
主分类号 |
C12N15/09 |
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