INHIBITION OF TUMOR GROWTH BY A NEMATODE ANTICOAGULANT PROTEIN
摘要
The present invention relates to compositions and uses of nematode anticoagulant proteins (NAPs). More specifically, the invention relates to the use of rNAPc2 and rNAP5 for the inhibition of endothelial cell proliferation and the inhibition of angiogenesis. The invention also relates to methods for the treatment of angiogenesis-mediated diseases, such as cancer.
申请公布号
WO0204010(A3)
申请公布日期
2003.07.31
申请号
WO2001US22231
申请日期
2001.07.12
申请人
ENTREMED, INC.;GREEN, SHAWN, J.;HEMBROUGH, TODD, A.