| 摘要 |
The invention relates to a method for the production of 7-dehydrocholesterol and/or the biosynthetic intermediate or subsequent products thereof by the cultivation of organisms, in particular, yeasts which show an increased activity of at least one activity, selected from delta-8/delta-7 isomerisation activity, delta-5 desaturase activity or delta-24 reductase activity. The invention further relates to the nucleic acid constructs necessary for production of the genetically-modified organisms and the genetically-modified organisms, in particular, the yeasts themselves. |
