发明名称 |
Inhibition of RNA function by delivery of inhibitors to animal cells |
摘要 |
Described is a process for delivering an inhibitor directed against an expressible nucleic acid sequence in a mammal to inhibit RNA function. An RNA function inhibiting sequence that is specific to the expressible nucleic acid sequence in the mammal is made and inserted into a blood vessel in the mammal. The inhibitor is delivered to a cell wherein expression of the nucleic acid sequence is inhibited.
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申请公布号 |
US2003143204(A1) |
申请公布日期 |
2003.07.31 |
申请号 |
US20020186757 |
申请日期 |
2002.07.01 |
申请人 |
LEWIS DAVID L.;HAGSTROM JAMES E.;HERWEIJER HANS;LOOMIS AARON G.;MONAHAN SEAN D.;TRUBETSKOY VLADIMIR S.;WOLFF JON A. |
发明人 |
LEWIS DAVID L.;HAGSTROM JAMES E.;HERWEIJER HANS;LOOMIS AARON G.;MONAHAN SEAN D.;TRUBETSKOY VLADIMIR S.;WOLFF JON A. |
分类号 |
A61K31/58;A61K31/74;A61K38/00;A61K48/00;C12N15/11;C12N15/113;C12N15/88;(IPC1-7):A61K48/00;C12N15/86 |
主分类号 |
A61K31/58 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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