发明名称 |
POLYMERIC GEL SYSTEM FOR THE CONTROLLED DELIVERY OF CODRUGS |
摘要 |
Implantable, injectable, insertable, or otherwise administrable compositions that form hydrogels when implanted, injected, inserted, or administered into or onto living tissues comprise a pharmaceutically effective compound wherein the pharmaceutically effective compound is a codrug, or pharmaceutically acceptable salt or prodrug thereof in admixture with a hydrogel-forming compound. The pharmaceutically effective compound may be any compound that is soluble in bodily fluids, or that forms bodily fluid-soluble adducts when exposed to bodily fluids. Exemplary compounds include analgesic, anti-inflammatory and antibiotic compounds. The hydrogel-forming compound is a biologically tolerated substance that forms a hydrogel upon exposure to bodily fluids, such as the interstitial fluid surrounding or within a joint.
|
申请公布号 |
WO03061626(A1) |
申请公布日期 |
2003.07.31 |
申请号 |
WO2003US01906 |
申请日期 |
2003.01.21 |
申请人 |
CONTROL DELIVERY SYSTEMS, INC.;ASHTON, PAUL;CHEN, JIANBING |
发明人 |
ASHTON, PAUL;CHEN, JIANBING |
分类号 |
A61K9/20;A61K9/00;A61K9/16;A61K9/48;A61K31/485;A61K45/08;A61K47/08;A61K47/12;A61K47/32;A61K47/34;A61K47/36;A61K47/38;A61K47/42;A61P9/00;A61P25/02;A61P25/04;A61P25/06;A61P27/06;A61P29/00;A61P31/04;A61P31/12;A61P35/00;A61P37/02;A61P43/00;(IPC1-7):A61K9/00;A61K45/06;A61K47/48 |
主分类号 |
A61K9/20 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|