发明名称 |
METHODS AND COMPOSITIONS UTILIZING RAD51 |
摘要 |
In accordance with the objects outlined above, the present invention provides methods of diagnosing individuals at risk for a disease state which results in aberrant Rad51 loci. The methods comprise determining the distribution of Rad51 foci in a first tissue type of a first individual, and then comparing the distribution to the distribution of Rad51 foci from a second normal tissue type from the first individual or a second unaffected individual. A difference in the distributions indicates that the first individual is at risk for a disease state which results in aberrant Rad51 loci. Preferred disease states include cancer and disease states associated with apoptosis.
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申请公布号 |
US2003143533(A1) |
申请公布日期 |
2003.07.31 |
申请号 |
US19980182102 |
申请日期 |
1998.10.27 |
申请人 |
HAAF THOMAS;GOLUB EFIM ILYA;REDDY GURUCHARAN;RADDING CHARLES MEYER;WARD DAVID C. |
发明人 |
HAAF THOMAS;GOLUB EFIM ILYA;REDDY GURUCHARAN;RADDING CHARLES MEYER;WARD DAVID C. |
分类号 |
C07K14/47;C07K16/18;G01N33/15;G01N33/50;G01N33/574;(IPC1-7):C12Q1/68;G01N33/48;C07H21/00 |
主分类号 |
C07K14/47 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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