| 发明名称 |
POLYMORPHIC FORMS/HYDRATES OF N-[4-(3-CHLORO-4-FLUOROPHENYLAMINO)-7-(3-MORPHOLIN-4-YLPROPOXY)-QUI NAZOLIN-6-YL]ACRYLAMIDE DIHYDROCHLORIDE |
| 摘要 |
There are described polymorphic forms/hydrates of N-[4-(3-chloro-4-fluorophenylamino)-7-(3-morpholin-4-ylpropoxy)-qu inazolin-6-yl]-acrylamide dihydrochloride, processes for their preparation, as well as the use of the same for the preparation of medicaments with irreversible tyrosine kinase inhibiting action. 23 claims, 12 figures |
| 申请公布号 |
BG107352(A) |
申请公布日期 |
2003.07.31 |
| 申请号 |
BG20020107352 |
申请日期 |
2002.12.04 |
| 申请人 |
GODECKE GMBH |
发明人 |
BARTH, HUBERT;STEINER, KLAUS;SCHNEIDER, SIMON;HULS, DIETMAR;MUHLENFELD, ANDREAS;WESTERMAYER, MANFRED |
| 分类号 |
A61K31/517;A61P9/00;A61P9/10;A61P15/00;A61P17/06;A61P35/00;A61P43/00;C07D239/94;(IPC1-7):C07D239/94 |
主分类号 |
A61K31/517 |
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