发明名称 COMPOUNDS FOR MODULATING CELL PROLIFERATION
摘要 The following compounds of formulae (I) and (III) which may be useful in treating a variety of cell proliferative disorders are disclosed: Fomula (I) , (II), wherein R1, R2 and R3 are each independently selected from H, OH, C1- 6alkyl, C1-6 alkoxy, NH2, NH-C1-6alkyl, N(C1-6alkyl)(C1-6 alkyl), SH, S-C1-6 alkyl, NO2, CF3, OCF3 and halo; R4 is unsubstituted Ar, or Ar substituted wi th 1-4 substituents, independently selected from C1-6alkyl, C1-6 alkoxy and hal o; X is selected from (CH2CH2O)n and (CH2)n, and n=1-4.
申请公布号 CA2473763(A1) 申请公布日期 2003.07.31
申请号 CA20032473763 申请日期 2003.01.17
申请人 THE HOSPITAL FOR SICK CHILDREN 发明人 DEMIN, PETER;GRUNBERGER, THOMAS;ROUNOVA, OLGA;CIMPEAN, OCTAVIAN, LAURAND;ROIFMAN, CHAIM, M.
分类号 C07D213/70;A61K31/165;A61K31/216;A61K31/222;A61K31/265;A61K31/277;A61K31/4402;A61P35/00;A61P35/02;C07C255/23;C07C255/38;C07C255/41;C07C309/67;C07C309/73;C07C317/44;C07C317/46;(IPC1-7):C07C255/41 主分类号 C07D213/70
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