摘要 |
The following compounds of formulae (I) and (III) which may be useful in treating a variety of cell proliferative disorders are disclosed: Fomula (I) , (II), wherein R1, R2 and R3 are each independently selected from H, OH, C1- 6alkyl, C1-6 alkoxy, NH2, NH-C1-6alkyl, N(C1-6alkyl)(C1-6 alkyl), SH, S-C1-6 alkyl, NO2, CF3, OCF3 and halo; R4 is unsubstituted Ar, or Ar substituted wi th 1-4 substituents, independently selected from C1-6alkyl, C1-6 alkoxy and hal o; X is selected from (CH2CH2O)n and (CH2)n, and n=1-4.
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申请人 |
THE HOSPITAL FOR SICK CHILDREN |
发明人 |
DEMIN, PETER;GRUNBERGER, THOMAS;ROUNOVA, OLGA;CIMPEAN, OCTAVIAN, LAURAND;ROIFMAN, CHAIM, M. |