| 发明名称 |
Therapeutic methods using catalytic antibodies |
| 摘要 |
<p>Antigens capable of eliciting antibodies which can catalyze chemical reactions, in particular, the cleavage or formation of a peptide linkage, comprising a hapten or a hapten and a suitable carrier molecule are disclosed. Antibodies capable of cleaving or forming an amide, peptide, ester of glycosidic bond and which are elicited by such antigens are disclosed. Pharmaceutical uses of antibodies are disclosed including antibodies against renin, HIV coat protein, LPS TNF and IgE. <IMAGE></p> |
| 申请公布号 |
EP0701818(B1) |
申请公布日期 |
2003.07.30 |
| 申请号 |
EP19950111577 |
申请日期 |
1989.05.04 |
| 申请人 |
IGEN INTERNATIONAL, INC. |
发明人 |
POWELL, MICHAEL J.;MASSEY, RICHARD J.;REES, ANTHONY R. |
| 分类号 |
A61K38/00;A61K31/00;A61K38/43;A61K39/00;A61K39/385;A61K39/395;A61P9/12;A61P31/00;A61P31/04;A61P31/12;A61P31/18;A61P35/00;A61P37/00;A61P37/08;A61P43/00;C07C205/00;C07C229/46;C07C229/48;C07C235/74;C07C235/78;C07C235/80;C07C271/24;C07C311/06;C07C317/44;C07D205/085;C07D207/20;C07D207/40;C07D207/404;C07F7/08;C07F9/24;C07F9/30;C07F9/32;C07F9/40;C07F9/44;C07F9/553;C07F9/572;C07F9/6584;C07K5/08;C07K5/10;C07K7/06;C07K14/00;C07K14/76;C07K14/81;C07K16/00;C07K16/10;C07K16/44;C12N5/10;C12N9/00;C12N9/14;C12N9/16;C12N9/48;C12N15/02;C12N15/55;C12P21/08;C12Q1/25;C12R1/91;G01N33/531;G01N33/577;(IPC1-7):A61K39/395 |
主分类号 |
A61K38/00 |
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