The present invention discloses synthetic oligonucleotides complementary to contiguous and non-contiguous regions of the HCV RNA. Also disclosed are methods and kits for inhibiting the replication of HCV, inhibiting the expression of HCV nucleic acid and protein, and for treating HCV infections.
申请公布号
EP1331267(A2)
申请公布日期
2003.07.30
申请号
EP20030005364
申请日期
1996.06.04
申请人
HYBRIDON, INC.
发明人
FRANK, BRUCE L.;GOODCHILD, JOHN;HAMLIN, HENRY A., JR.;KULKUSKIE, ROBERT E.;ROBERTS, PETER C.;ROBERTS, NOEL A.;WALTHER, DEBRA M.;WOLFE, JIA L.
