发明名称 Process for preparing a multicombinatorial library of vectors for expressing antibody genes
摘要 On the basis of a first repertoire of genes coding for a population of one of two kinds of polypeptides capable of being combined, particularly an antibody light chain variable region, and at least one gene, and preferably a second repertoire coding for the other kind of polypeptide, particularly an antibody heavy chain variable region, the genes from the first repertoire are inserted into a first vector to form a vector population and the genes from the second repertoire are inserted into a second vector, at least one of said vectors being a recipient for the expression of both genes as polypeptides irreversibly combined with the outer surface of the product of said vector.
申请公布号 US6599697(B1) 申请公布日期 2003.07.29
申请号 US19960693234 申请日期 1996.10.04
申请人 PASTEUR MERIEUX SERUMS ET VACCINS 发明人 SODOYER REGIS;AUJAME LUC;GEOFFROY FREDERIQUE
分类号 C12N15/09;C07K16/00;C07K16/10;C12N15/10;C40B40/02;(IPC1-7):C12O1/70;C12O1/68;C12N15/00 主分类号 C12N15/09
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