发明名称 |
Immunologically based strip test utilizing ionophore membranes |
摘要 |
A testing apparatus 10 having an absorbent matrix 12, including a membrane 14 which contains a plurality of counter-ions 16. Chromionophore (or fluorionophore)s 18 and affinophores 22 compete to carry ions into the membrane 14 and neutralize the charge of the counter-ions 16. Biological recognition molecules 42 bind to a portion of the affinophores 22 and prevent them from entering the membrane 14, thereby allowing more chromionophore (or fluorionophore)s 18 to enter the membrane 14. The portion of affinophores 22 bound to the biological recognition molecules 42 is inversely proportional to the amount or concentration of analyte 40 occurring within the solution or medium 30. The result of this is that the color of the membrane-covered matrix changes in a manner related to the concentration of the analyte. One application of this apparatus is a strip test for prediction of ovulation.
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申请公布号 |
US6599708(B2) |
申请公布日期 |
2003.07.29 |
申请号 |
US20010885321 |
申请日期 |
2001.06.19 |
申请人 |
IA, INC. |
发明人 |
ERB JUDITH LOUISE;CHIDAMBARAM NALLAPERUMAL;DOWNWARD, IV JAMES GERMAIN |
分类号 |
G01N33/532;G01N33/543;G01N33/58;G01N33/74;(IPC1-7):G01N33/53;G01N33/558;G01N33/559;G01N33/537;C12Q1/00 |
主分类号 |
G01N33/532 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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