发明名称 |
PROCESS FOR THE PREPARATION OF N-(1,1-DIMETHYLETHYL)-4-[[5'-ETHOXY-4-CIS[2-(4-MORPHOLINO)ETHOXY]-2'-OXOSPIRO[CYCLOHEXAN-1,3'[H]INDOL]1'(2'-H)-YL]-SULFONYL]-3-METHOXYBENZAMIDE AND ITS SALTS |
摘要 |
The invention relates to a process for the preparation of a compound of formula (I) and the salts thereof by reacting the compound of formula (II) with the compound of formula (III), which comprises carrying out the reaction in dimethyl sulfoxide, at a temperature between 10° C. and 40° C., preferably at room temperature and transforming the resulting base of formula (I), if desired, into its salt by a method known per se.
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申请公布号 |
US6600039(B1) |
申请公布日期 |
2003.07.29 |
申请号 |
US20020030647 |
申请日期 |
2002.04.17 |
申请人 |
SANOFI-SYNTHELABO |
发明人 |
HEJA GERGELY;CSIKOS EVA;TAKACSY TUENDE EROESNE;GOENCZI CSABA;HALASZ JUDIT;HERMECZ ISTVAN;MAJLATH CSILLA;NAGY LAJOS;CSUTOR ANDREA SANTANE;SAROSI PETER;SIMON KALMAN;SZOMOR TIBORNE;SZVOBODA GYOERGYNE |
分类号 |
A61K31/5377;A61P5/12;C07B61/00;C07D209/96;(IPC1-7):C07D273/00 |
主分类号 |
A61K31/5377 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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